The threat of carcinogens in drinking water

Marek Pipal is a Toxicologist in our NCET team

Get in touch Get in touch

It's #TechnicalTuesday so #teamWRc toxicologist Marek Pípal is discussing the threat of carcinogens in drinking water.

The number of substances found in UK drinking water supply is increasing, with some substances posing a threat due to their genotoxic and carcinogenic properties. Combined with increasing societal awareness of exposure to harmful chemicals from different sources, there is increasing pressure on regulators and water providers to deliver wholesome water quality and maintain a high level of trust for UK consumers.

The National Centre for Environmental Toxicology (NCET) at WRc Group conducts a risk assessment for compounds that are potentially carcinogenic with genotoxic activity (the ability to cause alterations to DNA potentially leading to mutations). The presence of these compounds makes risk management and communication of risks to consumers more difficult. For such chemicals, the Margin of Exposure approach (MOE) can be used by risk managers to aid the prioritisation of chemicals and to facilitate the communication of the risks associated with genotoxic chemical carcinogens. MOE can also help to evaluate the added risk in cases where exposure is unavoidable or identify the most sensitive groups within the population for effective public health management. The approach provides a specific response to the detected concentration of genotoxic compounds contrary to the commonly used recommendation in UK: As Low As Reasonably Practicable.

Created by potrace 1.16, written by Peter Selinger 2001-2019

Have your say

Head over to the WRc LinkedIn channel to join the conversation and share your thoughts with your network.

React, comment and share

Created by potrace 1.16, written by Peter Selinger 2001-2019

Start a conversation

Full name
Email address
Company name
How can we help?

Can we stay in touch?

Your details will be stored within our CRM to allow us to handle your enquiry. We'd love to keep in touch and send you our newsletters and other notifications we think may be of interest to you. Please let us know if we have your permission for this.

Marek Pipal


Marek is a toxicologist working at NCET, WRc with a PhD in Environmental Chemistry and Toxicology. He has experience with different aspects of (eco)toxicology: from experimental design and data assessment to environmental risk assessment and publication, as well as regulatory applications working for agrochemical companies. He has also delivered work for agrochemical companies preparing plant protection products dossiers, being the principal person for conducting literature review according to requirements set up in Directive 1107/2011/EC.

2022-10-11 10:02:00