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New Approach Methodologies (NAMs) Toxicology

WRC’s team at the National Centre of Environmental Toxicology helps clients to adopt modern toxicology strategies with confidence through the provision of NAM-based approach that supports reduced reliance on animal testing, cost effective and timely toxicological assessment, and alignment with the future direction of regulatory toxicology.

Dr Ehi Idahosa-Taylor is our expert in NAMs Toxicology

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Future Ready Toxicology Solutions

We provide expert toxicology consultancy services using New Approach Methodologies (NAMs) to support confident, efficient, and sustainable decision making. By analysing in silico data, we deliver regulatory-relevant toxicological evaluations while reducing the time, cost, and ethical burden associated with traditional animal testing. This capability is complemented by expertise in integrated drug discovery, molecular modelling, predictive safety sciences, and data-driven approaches to support pharmaceutical and biotechnology research and development.

Our NAMs services help organisations modernise their toxicology, safety assessment, and discovery strategies while maintaining scientific rigour and regulatory credibility.

    Scientifically Robust, Regulatory Aligned NAMs Expertise

    Our NAMs computational toxicology, predictive safety, and integrated discovery services are grounded in established scientific principles and aligned with current regulatory thinking on alternative methods. We focus on transparency, traceability, and fit for purpose application to ensure assessments are clear, defensible, and decision-relevant.

    Services are tailored to the specific research question, discovery stage, use context, exposure scenario, and regulatory objective.

      Client-centered consultancy services

      NCET's helpful and informative team deliver concise, easily-understood reports to educate, guide and explain clients' obligations.

      Whenever, wherever you need us

      NCET provide a 27/4 Toxicology on Demand service entrusted by leading water utility companies.

      Providers of independent advice

      Advising on your toxicology issues is always based on honesty and transparency.

      Ensuring regulatory compliance

      NCET interpret regulatory guidance on risk assessment requirements for our clients, minimising corporate risks associated with non-compliance.

      NAMs-Based Hazard Identification

      • NAMs-Based Hazard Identification

      We support hazard identification and characterisation, target assessment, and early-stage discovery decision-making using alternative data streams that provide insight into biological effects and molecular mechanisms across a range of toxicological endpoints.

      Technical capabilities include:

      • Systematic collection and critical appraisal of existing toxicological, pharmacological, and biological data
      • Application of in silico methods, including QSAR, read-across, molecular modelling, and virtual screening approaches
      • Weight of evidence hazard characterisation and predictive safety assessment.

      All conclusions are supported by transparent scientific rationale, with uncertainties clearly described.

      Independent and trusted advisors

      NCET is the UK's leading independent advisor on the risks posed by chemicals, micro-organisms, and other naturally occurring and man-made substances to the environment.

      NCET's services are heavily relied upon by regulators; we work across chemicals, consumer and industrial products, cosmetics, pharmaceuticals, and emerging technologies, providing NAMs toxicology, and integrated discovery and safety assessment from early development through to regulatory submission.

      Get in touch via the contact form at the bottom of this page to enquire about our subscription service: Toxicology on Demand.

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      If you would like more information about any of our products or services, or have a question please don't hesitate to get in touch. One of our friendly team will get back to you promptly.

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      Dr Ehi Idahosa-Taylor

      Principal Toxicologist

      Ehi leads WRc's toxicology team to undertake research into chemical and environmental hazards to underpin policy and carries out assessments to determine the potential chemical or environmental risks associated with exposures to chemicals, with particular emphasis on supporting the UK water industry.

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