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Toxicology and Human Health Risk Assessment

At WRc NCET, our desk-based toxicology and human health risk assessment service provides robust, evidence-based evaluation of chemical risks to human health. We support regulatory submissions, site investigations, and product stewardship by interpreting toxicological data and applying recognised risk assessment frameworks.

Dr Ehi Idahosa-Taylor is our expert in Toxicology and Human Health Risk Assessment

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We deliver comprehensive desk-based toxicological risk assessments using peer-reviewed scientific literature, regulatory guidance, and authoritative databases. Our approach aligns with UK and international frameworks including UK REACH, ECHA guidance, and WHO recommendations.

What We Offer

Compilation and review of toxicological data

  • Derivation and refinement of health-based guidance values (e.g. DNELs, TDI, RfD, drinking water guideline values)
  • Human exposure assessment across relevant pathways (ingestion, dermal, inhalation)
  • Quantitative human health risk characterisation (including chemical mixture toxicity assessment)
  • Screening-level and detailed risk assessment for contaminants in soil, water and air
  • Support for contaminated land risk assessments (CLEA-aligned)
  • Interpretation of monitoring data and exceedances against regulatory thresholds
  • Preparation of regulator-ready technical reports

    Client-centered consultancy services

    NCET's helpful and informative team deliver concise, easily-understood reports to educate, guide and explain clients' obligations.

    Whenever, wherever you need us

    NCET provide a 27/4 Toxicology on Demand service entrusted by leading water utility companies.

    Providers of independent advice

    Advising on your toxicology issues is always based on honesty and transparency.

    Ensuring regulatory compliance

    NCET interpret regulatory guidance on risk assessment requirements for our clients, minimising corporate risks associated with non-compliance.

    Our Approach

    Our assessments follow a structured risk-based methodology:

    • Problem formulation – defining receptors, pathways and scenarios
    • Hazard identification – reviewing toxicological evidence and mode of action
    • Dose-response assessment – identifying critical thresholds
    • Exposure assessment – estimating realistic and worst-case exposures
    • Risk characterisation – integrating data to quantify risk and uncertainty
    • Interpretation – providing clear conclusions and recommendations





    Independent and trusted advisors

    NCET is the UK's leading independent advisor on the risks posed to the environment by chemicals, micro-organisms and other naturally occurring and man-made substances.

    NCET's services are heavily relied upon by regulators; we support UK water companies and provide out-of-hours enquiries and toxicological consultancy service to the Omani Nama Water Services (NWS).

    Get in touch via the contact form at the bottom of this page to enquire about our subscription service: Toxicology on Demand

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      If you would like more information about any of our products or services, or have a question please don't hesitate to get in touch. One of our friendly team will get back to you promptly.

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      Dr Ehi Idahosa-Taylor

      Principal Toxicologist

      Ehi leads WRc's toxicology team to undertake research into chemical and environmental hazards to underpin policy and carries out assessments to determine the potential chemical or environmental risks associated with exposures to chemicals, with particular emphasis on supporting the UK water industry.

      Get in touch